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KMID : 0377519830080040405
Chung-Ang Journal of Medicine
1983 Volume.8 No. 4 p.405 ~ p.409
Morphological Study on the Possible Pathogenesis of Pterygium
Lee Yoong-Moon

Koo Bon-Sool
Abstract
Specimens of 89 cases of pterygia in adult patients were thoroughly examined with light and electron-microscope. In addition to H & E staining, PAS, Masson trichrome, Goldswithch¡¯s and Verhoeff¡¯s special stainings were conducted. Interpretation of histopathological findings on the abnormal tissues in relation to the patients age groups ad the duration of disease course enabled to conclude as follows: 1. Histopathological alterations in the pterygia were encountered throughout the tissues of the conjunctival epithelium, immediate subepithelial layer and deep layer of substantia propria as well. 2. The concept of "senile elastosis" as the compatible term of the specific finding of pterygium was deniable since the process of tissue alteration in patient did not concurrently progress with aging. 3. Relatively early occurrence of elastodysplasia in deep layer of substantia propria lead to indicate the possibility of primary lesion in combination of activity of fibrocytes in vicinity induced by various factors including the hereditary disposition. 3. Histopathological changes in epithelial and subepithelial hyalinization appeared to be secondary alterations.
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